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Unc5a/UNC5H1 Antibody, HRP Conjugated

Unc5a/UNC5H1 Antibody, HRP Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name HRP Conjugated, Unc5a/UNC5H1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUnc5a/UNC5H1
SpecificityThis is a highly specific antibody against Unc5a/UNC5H1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Unc5a
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additionally, In the absence of netrin-1, The expression of UNC5H receptors is downregulated in multiple carcinomas, This activity is blocked by the binding of netrin-1, Three isoforms of UNC5H1 exist due to alternative splicing events, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, UNC5H1, also known as UNC5HA (unc-5 homolog A), breast, but mutation of these receptors provides a potential mechanism for tumorigenicity, including colorectal, is a member of the UNC5H family of proteins and is localized to the cell membrane, lung and kidney cancers, ovary, stomach, uterus, when cleaved by a caspase to produce an intracellular fragment containing a death domain, The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells, UNC5H receptors induce apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms KIAA1976 UNC5H1
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetUnc5a/UNC5H1 Conjugated
Short name Conjugated, Unc5a/UNC5H1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name elegans)/UNC5H1 (Antibody to), horseradish peroxidase coupled, unc-5 homolog A (C
Alternative techniqueantibodies
Identity 12567
Gene UNC5A
Long gene name unc-5 netrin receptor A
Synonyms gene name elegans) , unc5 (C, elegans homolog) a unc-5 homolog A (C
Locus 5q35, 2
Discovery year 1998-12-09
GenBank acession AB075856
Entrez gene record 90249
Pubmed identfication 12655055 20372800
RefSeq identity XM_030300
Classification I-set domain containing
Havana BLAST/BLAT OTTHUMG00000163225

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