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UNC5D/UNC5H4 Antibody

UNC5D/UNC5H4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUNC5D/UNC5H4 Primary Polyclonal Antibody
Also known asUNC5D/UNC5H4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUNC5D/UNC5H4
SpecificityThis is a highly specific antibody against UNC5D/UNC5H4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UNC5H4
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, In the absence of netrin-1, The expression of UNC5H receptors is down-regulated in multiple carcinomas, This activity is blocked by the binding of netrin-1, Two isoforms of UNC5H4 exist due to alternative splicing events, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, UNC5H4, also known as UNC5D (unc-5 homolog D), and kidney cancers, breast, but mutation of these receptors provides a potential mechanism for tumorigenicity, including colorectal, is single-pass type I membrane protein that is a member of the UNC5H netrin receptor family, lung, ovary, stomach, uterus, when cleaved by a caspase to produce an intracellular fragment containing a death domain, The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells, UNC5H receptors induce apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FLJ16019, KIAA1777, Netrin receptor Unc5h4, Protein unc 5 homolog D, UNC 5D, Unc 5 homolog 4, Unc 5 homolog D, Unc 5 homolog D C, Unc5h4, elegans, Netrin receptor UNC5D
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUNC5D/UNC5H4
Short nameUNC5D/UNC5H4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name elegans)/UNC5H4 (Antibody to), unc-5 homolog D (C
Alternative techniqueantibodies
Alternative to gene target Cell surfaces, UNC5D and IDBG-16693 and ENSG00000156687 and 137970, UNC5D and IDBG-628993 and ENSBTAG00000010241 and 520004, Unc5d and IDBG-146351 and ENSMUSG00000063626 and 210801, elegans), protein binding, this GO :0005515 and protein binding and molecular function this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0021859 and pyramidal neuron differentiation and biological process this GO :2001222 and regulation of neuron migration and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, unc-5 homolog D (C
Identity 18634
Gene UNC5D
Long gene name unc-5 netrin receptor D
Synonyms gene name elegans) , unc-5 homolog D (C
Synonyms KIAA1777 Unc5h4
Synonyms name Netrin receptor UNC5D Protein unc-5 homolog 4 Protein unc-5 homolog D
Locus 8p12
Discovery year 2002-05-13
GenBank acession AB055056
Entrez gene record 137970
Pubmed identfication 18402767
Classification I-set domain containing
Havana BLAST/BLAT OTTHUMG00000157145

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