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UNC5D/UNC5H4 Antibody, ALEXA FLUOR 555

UNC5D/UNC5H4 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, UNC5D/UNC5H4 Polyclonal Antibody
Also known asAnti-UNC5D/UNC5H4 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUNC5D/UNC5H4
SpecificityThis is a highly specific antibody against UNC5D/UNC5H4
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UNC5H4
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Additionally, In the absence of netrin-1, The expression of UNC5H receptors is down-regulated in multiple carcinomas, This activity is blocked by the binding of netrin-1, Two isoforms of UNC5H4 exist due to alternative splicing events, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, UNC5H4, also known as UNC5D (unc-5 homolog D), and kidney cancers, breast, but mutation of these receptors provides a potential mechanism for tumorigenicity, including colorectal, is single-pass type I membrane protein that is a member of the UNC5H netrin receptor family, lung, ovary, stomach, uterus, when cleaved by a caspase to produce an intracellular fragment containing a death domain, The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells, UNC5H receptors induce apoptosis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms KIAA1777 Unc5h4
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetUNC5D/UNC5H4
Short nameUNC5D/UNC5H4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, elegans)/UNC5H4 (Antibody to), unc-5 homolog D (C
Alternative techniqueantibodies
Alternative to gene target Cell surfaces, UNC5D and IDBG-16693 and ENSG00000156687 and 137970, UNC5D and IDBG-628993 and ENSBTAG00000010241 and 520004, Unc5d and IDBG-146351 and ENSMUSG00000063626 and 210801, elegans), protein binding, this GO :0005515 and protein binding and molecular function this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0021859 and pyramidal neuron differentiation and biological process this GO :2001222 and regulation of neuron migration and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, unc-5 homolog D (C
Identity 18634
Gene UNC5D
Long gene name unc-5 netrin receptor D
Synonyms gene name elegans) , unc-5 homolog D (C
Synonyms name Netrin receptor UNC5D Protein unc-5 homolog 4 Protein unc-5 homolog D
Locus 8p12
Discovery year 2002-05-13
GenBank acession AB055056
Entrez gene record 137970
Pubmed identfication 18402767
Classification I-set domain containing
Havana BLAST/BLAT OTTHUMG00000157145

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