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Unrip Antibody

Unrip Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUnrip Primary Polyclonal Antibody
Also known asUnrip PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUnrip
SpecificityThis is a highly specific antibody against Unrip
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Unrip
Gene ID number11171
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It is associated with the complex in the cytoplasm but not in the nucleus and thus is thought to play a role in it's subcellular localisation, It is the first component of the U snRNP assembly machinery that associates with SMN complex in a compartment-specific way and plays a crucial role in the intracellular distribution of SMN1, Stable expression of STRAP results in activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and in down-regulation of the cyclin-dependent kinase inhibitor p21 (Cip1), Unrip interacts directly with Gemin 6 and Gemin 7 in the SMN complex, Upregulation of STRAP might play a role in tumor development as an early event for colorectal cancers, which results in retinoblastoma protein hyperphosphorylation, It is a ubiquitously expressed protein that acts as an inhibitor of TGF-beta signaling and an important regulator of cell proliferation, Unrip is part of the SMN complex that plays a role in snRNP assembly in the cytoplasm and pre mRNA splicing in the nucleus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MAWD, PTWD, STRAP, STRAP_HUMAN, UNR-interacting protein, UNRIP, WD 40 repeat protein PT WD, serine/threonine kinase receptor associated protein, MAP activator with WD repeats
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUnrip
Short nameUnrip Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUnrip (Antibody to)
Alternative techniqueantibodies
Identity 30796
Gene STRAP
Long gene name serine/threonine kinase receptor associated protein
Synonyms UNRIP pt-wd MAWD
Synonyms name Unr-interacting protein
Locus 12p12, 3
Discovery year 2004-04-19
GenBank acession AB024327
Entrez gene record 11171
RefSeq identity NM_007178
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000168791

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