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uPAR Antibody uPA Receptor

uPAR Antibody uPA Receptor size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenuPAR uPA Receptor
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the uPAR antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis uPAR antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q03405
PurityAntigen affinity
Description In human coronary artery vascular smooth muscle cells, It binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane, It consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family, It is localized to 19q13, The gene plays an important role in many normal as well as pathologic processes, The protein was originally identified as a saturable binding site for urokinase on the cell surface, UPA stimulates cell migration via a uPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase, also known as uPAR or CD87, indicating it is an important player in the regulation of this process, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol(GPI) anchor, uPAR is a part of the plasminogen activation system, urokinase-type), which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing, 31, PLAUR (Plasminogen activator receptor
ImmunogenAn amino acid sequence from the C-terminus of human uPAR (CNHPDLDVQYRS) was used as the immunogen for this uPAR antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the uPAR antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetuPAR uPA Receptor
Short nameuPAR Antibody uPA Receptor
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameuPAR (Antibody to) uPA Receptor
Alternative techniqueantibodies

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