Name : Uromodulin Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2658516486
| Long name | ALEXA FLUOR 488 Conjugated, Uromodulin Polyclonal Antibody |
| Also known as | Anti-Uromodulin PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Uromodulin |
| Specificity | This is a highly specific antibody against Uromodulin |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 375-420/642 |
| Source | KLH conjugated synthetic peptide derived from mouse Uromodulin |
| Gene ID Number | 22242 |
| Swiss Prot | Q91X17 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Facilitates neutrophil migration across renal epithelial (By similarity), IL-2) and TNF, Into the urine, May serve as a receptor for binding and endocytosis for cytokines (IL-1, Uromodulin, may contribute to colloid osmotic pressure, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals, retards passage of positively charged electrolytes, secreted form: Secreted into urine after proteolytically cleaveage, where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability, Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Uromodulin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Uromodulin |
| Short name | Uromodulin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Uromodulin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12559 |
| Gene | UMOD |
| Long gene name | uromodulin |
| Synonyms gene name | Tamm-Horsfall glycoprotein) , uromodulin (uromucoid |
| Synonyms name | Tamm-Horsfall glycoprotein uromucoid |
| Locus | 16p12, 3 |
| Discovery year | 1992-07-27 |
| GenBank acession | M17778 |
| Entrez gene record | 7369 |
| Pubmed identfication | 8382593 |
| Havana BLAST/BLAT | OTTHUMG00000131488 |