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USP14 (889CT6.2.1) Monoclonal Antibody

USP14 (889CT6.2.1) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1) Monoclonal Antibody, 2, USP14 (889CT6
Also known as1) Monoclonal Antibody, 2, USP14 (889CT6
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUSP14
SpecificityThis is a highly specific antibody against USP14
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 2, 889CT6
SourcePurified His-tagged USP14 protein was used to produced this monoclonal antibody
Gene ID number9097
Swiss ProtP54578
Tested ApplicationsWB
Recommended dilutionsWB(1:1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Ensures the regeneration of ubiquitin at the proteasome, Indispensable for synaptic development and function at neuromuscular junctions (NMJs), Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell, Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis, Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1, Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins
Purification method This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Deubiquitinating enzyme 14, USP14, Ubiquitin carboxyl-terminal hydrolase 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, TGT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1) Monoclonal, 2, USP14 (889CT6
Short name1) Monoclonal Antibody, 2, USP14 (889CT6
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1) monoclonal (Antibody to), 2, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (889CT6
Alternative techniqueantibodies
Alternative to gene target BT, Cell surfaces, TGT, USP14 and IDBG-259 and ENSG00000101557 and 9097, Usp14 and IDBG-128322 and ENSMUSG00000047879 and 59025, proteasome binding, this GO :0000502 and proteasome complex and cellular component this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0004221 and ubiquitin thiolesterase activity and molecular function this GO :0004843 and ubiquitin-specific protease activity and molecular function this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0007268 and synaptic transmission and biological process this GO :0008193 and tRNA guanylyltransferase activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0009986 and cell surface and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016579 and protein deubiquitination and biological process this GO :0036459 and ubiquitinyl hydrolase activity and molecular function this GO :0045202 and synapse and cellular component this GO :0050920 and regulation of chemotaxis and biological process this GO :0061136 and regulation of proteasomal protein catabolic process and biological process this GO :0070628 and proteasome binding and molecular function, this GO :0004197: cysteine-type endopeptidase activity, this GO :0004197: cysteine-type endopeptidase activity and also this GO :0004221: ubiquitin thiolesterase activity and also this GO :0004843: ubiquitin-specific protease activity and also this GO :0004866: endopeptidase inhibitor activity and also this GO :0005515: protein binding and also this GO :0008193: tRNA guanylyltransferase activity and also this GO :0008234: cysteine-type peptidase activity and also this GO :0036459: ubiquitinyl hydrolase activity and also this GO :0070628: proteasome binding, this GO :0004221: ubiquitin thiolesterase activity, this GO :0004843: ubiquitin-specific protease activity, this GO :0004866: endopeptidase inhibitor activity, this GO :0005515: protein binding, this GO :0008193: tRNA guanylyltransferase activity, this GO :0008234: cysteine-type peptidase activity, this GO :0036459: ubiquitinyl hydrolase activity, this GO :0070628: proteasome binding, 20599 and IDBG-644085 and ENSBTAG00000019214 and 505106, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Identity 12612
Gene USP14
Long gene name ubiquitin specific peptidase 14
Synonyms gene name ubiquitin specific protease 14 (tRNA-guanine transglycosylase) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Synonyms TGT
Locus 18p11, 32
Discovery year 1999-02-01
GenBank acession U30888
Entrez gene record 9097
Pubmed identfication 12838346
RefSeq identity NM_005151
Classification Ubiquitin specific peptidases
Havana BLAST/BLAT OTTHUMG00000178040

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