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USP28 Antibody, Cy3 Conjugated

USP28 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, USP28 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUSP28
SpecificityThis is a highly specific antibody against USP28
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human USP28
Gene ID number57646
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also involved in G2 DNA damage checkpoint, In contrast, In contrast, Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN, Specifically deubiquitinates MYC in the nucleoplasm, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C), by deubiquitinating CLSPN, it does not deubiquitinate PLK1, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex, Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms KIAA1515
Properties 1 of the USP28 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetUSP28 Conjugated
Short name Conjugated, USP28 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, ubiquitin specific peptidase 28 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, USP28 and IDBG-71844 and ENSG00000048028 and 57646, Usp28 and IDBG-162407 and ENSMUSG00000032267 and 235323, nuclei, this GO :0000077 and DNA damage checkpoint and biological process this GO :0004221 and ubiquitin thiolesterase activity and molecular function this GO :0004843 and ubiquitin-specific protease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0006281 and DNA repair and biological process this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0016579 and protein deubiquitination and biological process this GO :0034644 and cellular response to UV and biological process this GO :0036459 and ubiquitinyl hydrolase activity and molecular function this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043234 and protein complex and cellular component, this GO :0004221: ubiquitin thiolesterase activity, this GO :0004221: ubiquitin thiolesterase activity and also this GO :0004843: ubiquitin-specific protease activity and also this GO :0005515: protein binding and also this GO :0008234: cysteine-type peptidase activity and also this GO :0036459: ubiquitinyl hydrolase activity, this GO :0004843: ubiquitin-specific protease activity, this GO :0005515: protein binding, this GO :0008234: cysteine-type peptidase activity, this GO :0036459: ubiquitinyl hydrolase activity, ubiquitinyl hydrolase activity, 24505 and IDBG-630659 and ENSBTAG00000002323 and 508902, ubiquitin specific peptidase 28
Identity 12625
Gene USP28
Long gene name ubiquitin specific peptidase 28
Synonyms gene name ubiquitin specific protease 28
Locus 11q23, 2
Discovery year 2000-05-26
GenBank acession AB040948
Entrez gene record 57646
Pubmed identfication 12838346 11597335
Classification Ubiquitin specific peptidases
Havana BLAST/BLAT OTTHUMG00000168205

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