Name : UVRAG Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3902724374
| Long name | ALEXA FLUOR 555 Conjugated, UVRAG Polyclonal Antibody |
| Also known as | Anti-UVRAG PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | UVRAG |
| Specificity | This is a highly specific antibody against UVRAG |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UVRAG/DHTX |
| Gene ID Number | 7405 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Autophagy is the degradation of cellular proteins in the lysosomes, Mutations in the gene encoding UVRAG have been associated with colon cancer, UVRAG contains one C2 domain, UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells, UVRAG has been shown to activate the BECN1/PI 3-kinase complex, UVRAG is found at highest levels in kidney, Ubiquitously expressed, also known as p63 or DHTX, and when this pathway is suppressed, cell growth is deregulated, is a 699 amino acid cytoplasmic protein, liver and brain, lung, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells, which is thought to be involved in calcium-dependent phospholipid binding, which promotes autophagy, UVRAG |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | VPS38 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | UVRAG |
| Short name | UVRAG Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, UVRAG (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12640 |
| Gene | UVRAG |
| Long gene name | UV radiation resistance associated |
| Synonyms gene name | UV radiation resistance associated gene |
| Synonyms name | beclin 1 binding protein |
| Locus | 11q13, 5 |
| Discovery year | 1997-01-10 |
| GenBank acession | X99050 AB012958 |
| Entrez gene record | 7405 |
| Pubmed identfication | 9169138 16799551 18843052 |
| RefSeq identity | NM_003369 |
| Classification | C2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000165319 |