Name : VAMP8 (1414CT354.12.23.93) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN1561597537
| Long name | 12, 23, 93) Monoclonal Antibody, VAMP8 (1414CT354 |
| Also known as | 12, 23, 93) Monoclonal Antibody, VAMP8 (1414CT354 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | VAMP8 |
| Specificity | This is a highly specific antibody against VAMP8 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 12, 1414CT354, 23, 93 |
| Source | This VAMP8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 2~24 amino acids from the N-terminal region of human VAMP8 |
| Gene ID number | 8673 |
| Swiss Prot | Q9BV40 |
| Tested Applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:25), WB(1:1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also required for dense-granule secretion in platelets (PubMed:12130530), Involved in the abscission of the midbody during cell division, Involved in the homotypic fusion of early and late endosomes (By similarity), Plays also a role in regulated enzyme secretion in pancreatic acinar cells (By similarity), PubMed:25686604), SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, an extended, are essential proteins for fusion of cellular membranes, parallel four alpha-helical bundle that drives membrane fusion, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, which leads to completely separate daughter cells (By similarity), SNAREs |
| Purification method | This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Endobrevin, VAMP-8, VAMP8, Vesicle-associated membrane protein 8, EDB |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 12, 23, 93) Monoclonal, VAMP8 (1414CT354 |
| Short name | 12, 23, 93) Monoclonal Antibody, VAMP8 (1414CT354 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 12, 23, 93) monoclonal (Antibody to), VAMP8 (1414CT354 |
| Alternative technique | antibodies |
| Identity | 12647 |
| Gene | VAMP8 |
| Long gene name | vesicle associated membrane protein 8 |
| Synonyms | EDB |
| Synonyms name | endobrevin |
| Locus | 2p11, 2 |
| Discovery year | 1998-11-30 |
| GenBank acession | AF053233 |
| Entrez gene record | 8673 |
| Pubmed identfication | 9878266 9614193 |
| RefSeq identity | NM_003761 |
| Classification | Vesicle associated membrane proteins |
| Havana BLAST/BLAT | OTTHUMG00000130180 |