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VDAC1 Antibody, Cy5 Conjugated

VDAC1 Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, VDAC1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenVDAC
Specificity May detect VDAC2 due to sequence similarity, This is a highly specific antibody against VDAC
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range95-130/283
Subcellular locationMitochondrion
SourceKLH conjugated synthetic peptide derived from human VDAC1
Gene ID number7416
Swiss ProtP21796
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis, The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, The open state has a weak anion selectivity whereas the closed state is cation-selective, in the plasma membrane it is involved in cell volume regulation and apoptosis, Forms a channel through the mitochondrial outer membrane and also the plasma membrane
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms MGC111064 PORIN
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetVDAC1 Conjugated
Short name Conjugated, VDAC1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, voltage-dependent anion channel 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target PORIN and VDAC-1, VDAC1 and IDBG-240337 and ENSG00000213585 and 7416, VDAC1 and IDBG-645740 and ENSBTAG00000013113 and 282119, Vdac1 and IDBG-171107 and ENSMUSG00000020402 and 22333, nuclei, porin activity, this GO :0001662 and behavioral fear response and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006820 and anion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007270 and neuron-neuron synaptic transmission and biological process this GO :0007612 and learning and biological process this GO :0008308 and voltage-gated anion channel activity and molecular function this GO :0015288 and porin activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0042645 and mitochondrial nucleoid and cellular component this GO :0044070 and regulation of anion transport and biological process this GO :0046930 and pore complex and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008308: voltage-gated anion channel activity and also this GO :0015288: porin activity, this GO :0008308: voltage-gated anion channel activity, this GO :0015288: porin activity, voltage-dependent anion channel 1
Identity 12669
Gene VDAC1
Long gene name voltage dependent anion channel 1
Locus 5q31, 1
Discovery year 1993-11-02
Entrez gene record 7416
Pubmed identfication 7517385
Classification Voltage dependent anion channels
Havana BLAST/BLAT OTTHUMG00000129118

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