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VE Cadherin Antibody (CDH5)

VE Cadherin Antibody (CDH5) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenVE Cadherin (CDH5)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, Western blot: 1:1000
NotesTitration of the VE Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis VE Cadherin antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P33151
PurityAntigen affinity
Description Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions, CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer
ImmunogenA portion of amino acids 106-134 from the human protein was used as the immunogen for this VE Cadherin antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the VE Cadherin antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetVE Cadherin (CDH5)
Short nameVE Cadherin Antibody (CDH5)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name type 2 (vascular endothelium)), VE Cadherin (Antibody to) (cadherin 5
Alternative techniqueantibodies
Alternative to gene target 7B4 and CD144, BT, CDH5 and IDBG-34871 and ENSG00000179776 and 1003, Cdh5 and IDBG-185038 and ENSMUSG00000031871 and 12562, Cell surfaces, ion channel binding, this GO :0001955 and blood vessel maturation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019903 and protein phosphatase binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045216 and cell-cell junction organization and biological process this GO :0071944 and cell periphery and cellular component this GO :2000114 and regulation of establishment of cell polarity and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0019903: protein phosphatase binding and also this GO :0044325: ion channel binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008013: beta-catenin binding, this GO :0019903: protein phosphatase binding, this GO :0044325: ion channel binding, type 2 (vascular endothelium), 64659 and IDBG-633039 and ENSBTAG00000007421 and 414735, cadherin 5
Identity 1764
Gene CDH5
Long gene name cadherin 5
Synonyms gene name VE-cadherin (vascular epithelium) cadherin 5, cadherin 5, type 2, type 2 (vascular endothelium)
Synonyms 7B4 CD144
Synonyms name VE-cadherin
Locus 16q21
Discovery year 1992-11-20
GenBank acession X79981
Entrez gene record 1003
Pubmed identfication 2059658
RefSeq identity NM_001795
Classification Type II classical cadherins CD molecules
Havana BLAST/BLAT OTTHUMG00000137495

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