| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | VEGFA |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the VEGFA antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This VEGFA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P15692 |
| Purity | Purified |
| Description | Elevated levels of this protein are linked to POEMS syndrome, Mutations in VEGFA have been associated with proliferative and nonproliferative diabetic retinopathy, This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, also known as Crow-Fukase syndrome, and inhibiting apoptosis, including mediating increased vascular permeability, inducing angiogenesis, promoting cell migration, vasculogenesis and endothelial cell growth, VEGFA is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer |
| Immunogen | A portion of amino acids 66-95 from the human protein was used as the immunogen for this VEGFA antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the VEGFA antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | VEGFA |
| Short name | VEGFA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | vascular endothelial growth factor A (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, MVCD1 and VEGF and VPF, VEGFA and IDBG-631944 and ENSBTAG00000047561 and 101904706, VEGFA and IDBG-88716 and ENSG00000112715 and 7422, Vegfa and IDBG-185847 and ENSMUSG00000023951 and 22339, extracellular matrix binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001525 and angiogenesis and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0001568 and blood vessel development and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001822 and kidney development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001944 and vasculature development and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0002040 and sprouting angiogenesis and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002052 and positive regulation of neuroblast proliferation and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0002575 and basophil chemotaxis and biological process this GO :0002576 and platelet degranulation and biological process this GO :0002687 and positive regulation of leukocyte migration and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003169 and coronary vein morphogenesis and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005172 and vascular endothelial growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007399 and nervous system development and biological process this GO :0007498 and mesoderm development and biological process this GO :0007595 and lactation and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009986 and cell surface and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030141 and secretory granule and cellular component this GO :0030168 and platelet activation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0030225 and macrophage differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031077 and post-embryonic camera-type eye development and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031334 and positive regulation of protein complex assembly and biological process this GO :0031954 and positive regulation of protein autophosphorylation and biological process this GO :0032147 and activation of protein kinase activity and biological process this GO :0032793 and positive regulation of CREB transcription factor activity and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0035148 and tube formation and biological process this GO :0035767 and endothelial cell chemotaxis and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0036303 and lymph vessel morphogenesis and biological process this GO :0038033 and positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway and biological process this GO :0038084 and vascular endothelial growth factor signaling pathway and biological process this GO :0038091 and positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway and biological process this GO :0038190 and VEGF-activated neuropilin signaling pathway and biological process this GO :0038191 and neuropilin binding and molecular function this GO :0040007 and growth and biological process this GO :0042056 and chemoattractant activity and molecular function this GO :0042462 and eye photoreceptor cell development and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043117 and positive regulation of vascular permeability and biological process this GO :0043129 and surfactant homeostasis and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043183 and vascular endothelial growth factor receptor 1 binding and molecular function this GO :0043184 and vascular endothelial growth factor receptor 2 binding and molecular function this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043536 and positive regulation of blood vessel endothelial cell migration and biological process this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048469 and cell maturation and biological process this GO :0048514 and blood vessel morphogenesis and biological process this GO :0048593 and camera-type eye morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048739 and cardiac muscle fiber development and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048842 and positive regulation of axon extension involved in axon guidance and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0050918 and positive chemotaxis and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0051272 and positive regulation of cellular component movement and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060319 and primitive erythrocyte differentiation and biological process this GO :0060426 and lung vasculature development and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0060754 and positive regulation of mast cell chemotaxis and biological process this GO :0060948 and cardiac vascular smooth muscle cell development and biological process this GO :0060982 and coronary artery morphogenesis and biological process this GO :0061418 and regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0061419 and positive regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071542 and dopaminergic neuron differentiation and biological process this GO :0071679 and commissural neuron axon guidance and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :0090050 and positive regulation of cell migration involved in sprouting angiogenesis and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :0090259 and regulation of retinal ganglion cell axon guidance and biological process this GO :1900086 and positive regulation of peptidyl-tyrosine autophosphorylation and biological process this GO :1900745 and positive regulation of p38MAPK cascade and biological process this GO :1901492 and positive regulation of lymphangiogenesis and biological process this GO :1901727 and positive regulation of histone deacetylase activity and biological process this GO :1902336 and positive regulation of retinal ganglion cell axon guidance and biological process this GO :1902533 and positive regulation of intracellular signal transduction and biological process this GO :1902966 and positive regulation of protein localization to early endosome and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0001968: fibronectin binding, this GO :0001968: fibronectin binding and also this GO :0005102: receptor binding and also this GO :0005125: cytokine activity and also this GO :0005161: platelet-derived growth factor receptor binding and also this GO :0005172: vascular endothelial growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0008201: heparin binding and also this GO :0038191: neuropilin binding and also this GO :0042056: chemoattractant activity and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043183: vascular endothelial growth factor receptor 1 binding and also this GO :0043184: vascular endothelial growth factor receptor 2 binding and also this GO :0046982: protein heterodimerization activity and also this GO :0048018: receptor a this GO nist activity and also this GO :0050840: extracellular matrix binding, this GO :0005102: receptor binding, this GO :0005125: cytokine activity, this GO :0005161: platelet-derived growth factor receptor binding, this GO :0005172: vascular endothelial growth factor receptor binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0008201: heparin binding, this GO :0038191: neuropilin binding, this GO :0042056: chemoattractant activity, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0043183: vascular endothelial growth factor receptor 1 binding, this GO :0043184: vascular endothelial growth factor receptor 2 binding, this GO :0046982: protein heterodimerization activity, this GO :0048018: receptor a this GO nist activity, this GO :0050840: extracellular matrix binding, vascular endothelial growth factor A |
| Identity | 12680 |
| Gene | VEGFA |
| Long gene name | vascular endothelial growth factor A |
| Synonyms gene | VEGF |
| Synonyms gene name | vascular endothelial growth factor |
| Synonyms | VEGF-A VPF |
| Locus | 6p21, 1 |
| Discovery year | 1994-01-10 |
| GenBank acession | AB021221 |
| Entrez gene record | 7422 |
| Pubmed identfication | 8786112 |
| RefSeq identity | NM_001025366 |
| Classification | VEGF family |
| Havana BLAST/BLAT | OTTHUMG00000014745 |
| Locus Specific Databases | ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |