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VEGFR2(Tyr951) Antibody, Cy3 Conjugated

VEGFR2(Tyr951) Antibody, Cy3 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, VEGFR2(Tyr951) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenVEGFR2 Tyr951
SpecificityThis is a highly specific antibody against VEGFR2 Tyr951
ModificationPhosphorylation
Modification siteTyr951
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range930-970/1356
Subcellular locationIntracellular
SourceKLH cunjugated synthetic phosphopeptide derived from human VEGFR2 around the phosphorylation site of Tyr951
Gene ID number3791
Swiss ProtP35968
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1, Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades, Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4, Isoforms lacking a transmembrane domain, MAPK3/ERK1 and the MAP kinase signaling pathway, Mediates activation of MAPK1/ERK2, Mediates phosphorylation of PIK3R1, Modulates FLT1 and FLT4 signaling by forming heterodimers, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC, Phosphorylates PLCG1, Plays an essential role in the regulation of angiogenesis, Promotes phosphorylation of FYN, Promotes proliferation, Promotes reorganization of the actin cytoskeleton, Required for VEGFA-mediated induction of NOS2 and NOS3, VEGFC and VEGFD, VEGFC and/or VEGFD, and embryonic hematopoiesis, as well as of the AKT1 signaling pathway, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells, may function as decoy receptors for VEGFA, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton and activation of PTK2/FAK1, such as isoform 2 and isoform 3, survival, the regulatory subunit of phosphatidylinositol 3-kinase, vascular development, vascular permeability, 4, 5-trisphosphate and the activation of protein kinase C, Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms FLK1 VEGFR VEGFR2 CD309
Properties 1 of the VEGFR2(Tyr951) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetVEGFR2(Tyr951) Conjugated
Short name Conjugated, VEGFR2(Tyr951) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, VEGFR2(Tyr951) (Antibody to)
Alternative techniqueantibodies
Identity 6307
Gene KDR
Long gene name kinase insert domain receptor
Synonyms gene name kinase insert domain receptor (a type III receptor tyrosine kinase)
Synonyms name vascular endothelial growth factor receptor 2 fetal liver kinase 1
Locus 4q12
Discovery year 1991-07-10
GenBank acession AF035121
Entrez gene record 3791
Pubmed identfication 1417831
Classification I-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000128734
Locus Specific Databases The Globin Gene Server

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