Filters

VEGFR3 Antibody

VEGFR3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameVEGFR3 Primary Polyclonal Antibody
Also known asVEGFR3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenVEGFR3
SpecificityThis is a highly specific antibody against VEGFR3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range920-970/1363
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from mouse VEGFR3
Gene ID number14257
Swiss ProtP35917
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen MAPK3/ERK1 signaling pathway, Mediates activation of the MAPK1/ERK2, Mediates phosphorylation of PIK3R1, Modulates KDR signaling by forming heterodimers, Phosphorylates SHC1, Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', Promotes proliferation, Signaling by activated FLT4 leads to enhanced production of VEGFC, and of AKT1 at 'Ser-473', and of the AKT1 signaling pathway, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development, and regulates angiogenic sprouting, and to a lesser degree VEGFA, of MAPK8 and the JUN signaling pathway, survival and migration of endothelial cells, the regulatory subunit of phosphatidylinositol 3-kinase, thereby creating a positive feedback loop that enhances FLT4 signaling, Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AI323512, Flt-4, Flt4, Fms-like tyrosine kinase 4, Tyrosine-protein kinase receptor FLT4, VEGFR-3, VEGFR3, Vascular endothelial growth factor receptor 3, Chy
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetVEGFR3
Short nameVEGFR3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameVEGFR3 (Antibody to)
Alternative techniqueantibodies
Identity 3767
Gene FLT4
Long gene name fms related tyrosine kinase 4
Synonyms gene name fms-related tyrosine kinase 4
Synonyms VEGFR3 PCL
Locus 5q35, 3
Discovery year 1991-10-25
GenBank acession X68203
Entrez gene record 2324
Pubmed identfication 1319394
Classification I-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000130931

Similar products

Subscribe to our Newsletter