Name : VEGFR3 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN3050829030
| Long name | Cy3 Conjugated, VEGFR3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | VEGFR3 |
| Specificity | This is a highly specific antibody against VEGFR3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 920-970/1363 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse VEGFR3 |
| Gene ID number | 14257 |
| Swiss Prot | P35917 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | MAPK3/ERK1 signaling pathway, Mediates activation of the MAPK1/ERK2, Mediates phosphorylation of PIK3R1, Modulates KDR signaling by forming heterodimers, Phosphorylates SHC1, Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', Promotes proliferation, Signaling by activated FLT4 leads to enhanced production of VEGFC, and of AKT1 at 'Ser-473', and of the AKT1 signaling pathway, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development, and regulates angiogenic sprouting, and to a lesser degree VEGFA, of MAPK8 and the JUN signaling pathway, survival and migration of endothelial cells, the regulatory subunit of phosphatidylinositol 3-kinase, thereby creating a positive feedback loop that enhances FLT4 signaling, Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | VEGFR3 PCL |
| Properties | 1 of the VEGFR3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | VEGFR3 Conjugated |
| Short name | Conjugated, VEGFR3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, VEGFR3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3767 |
| Gene | FLT4 |
| Long gene name | fms related tyrosine kinase 4 |
| Synonyms gene name | fms-related tyrosine kinase 4 |
| Locus | 5q35, 3 |
| Discovery year | 1991-10-25 |
| GenBank acession | X68203 |
| Entrez gene record | 2324 |
| Pubmed identfication | 1319394 |
| Classification | I-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000130931 |