Name : VRK1 (1015CT2.1.1) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :354
SKU : GEN7893960000
| Long name | 1, 1) Monoclonal Antibody, VRK1 (1015CT2 |
| Also known as | 1, 1) Monoclonal Antibody, VRK1 (1015CT2 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | VRK1 |
| Specificity | This is a highly specific antibody against VRK1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 1, 1015CT2 |
| Source | Purified His-tagged VRK1 protein was used to produced this monoclonal antibody |
| Gene ID number | 7443 |
| Swiss Prot | Q99986 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:5000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts by mediating phosphorylation of downstream target protein, Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2, Phosphorylates ATF2 which activates its transcriptional activity, Phosphorylates BANF1: disrupts its ability to bind DNA, Phosphorylates casein and histone H3, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm, required to induce Golgi fragmentation, Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | PCH1A, Serine/threonine-protein kinase VRK1, VRK1, Vaccinia-related kinase 1, PCH1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 1) Monoclonal, VRK1 (1015CT2 |
| Short name | 1, 1) Monoclonal Antibody, VRK1 (1015CT2 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1, 1) monoclonal (Antibody to), VRK1 (1015CT2 |
| Alternative technique | antibodies |
| Identity | 12718 |
| Gene | VRK1 |
| Long gene name | vaccinia related kinase 1 |
| Locus | 14q32, 2 |
| Discovery year | 1997-06-12 |
| GenBank acession | AB000449 |
| Entrez gene record | 7443 |
| Pubmed identfication | 9344656 |
| RefSeq identity | NM_003384 |
| Havana BLAST/BLAT | OTTHUMG00000171459 |