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WAVE 1 Antibody, Cy3 Conjugated

WAVE 1 Antibody, Cy3 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy3 Conjugated, WAVE 1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenWAVE 1
SpecificityThis is a highly specific antibody against WAVE 1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human WAVE 1
Gene ID number8936
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases, The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac, They mediate Actin polymerization by cooperating with the Arp2/3 complex, WAVE1, WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility, is expressed primarily in the brain, thereby promoting the formation of Actin filaments, which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton, which is also designated SCAR (suppressor of cAR), while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes, WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms WAVE1 SCAR1 KIAA0269 WAVE
Properties 1 of the WAVE 1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetWAVE 1 Conjugated
Short name Conjugated, WAVE 1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, WAVE 1 (Antibody to)
Alternative techniqueantibodies
Identity 12732
Gene WASF1
Long gene name WAS protein family member 1
Synonyms gene name WAS protein family, member 1
Locus 6q21
Discovery year 1999-09-21
GenBank acession D87459
Entrez gene record 8936
Pubmed identfication 9843499 9889097
RefSeq identity NM_003931
Classification A-kinase anchoring proteins Wiskott-Aldrich Syndrome protein family
Havana BLAST/BLAT OTTHUMG00000015357

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