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WEE1 Antibody

WEE1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameWEE1 Primary Polyclonal Antibody
Also known asWEE1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenWEE1
SpecificityThis is a highly specific antibody against WEE1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range570-615/646
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WEE1
Gene ID number7465
Swiss ProtP30291
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A correlated decrease in protein level occurs at M/G1 phase, Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated, Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur, Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase, probably due to its degradation, Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names WEE1, WEE1hu, Wee1-like protein kinase, Wee1A kinase, WEE1A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetWEE1
Short nameWEE1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameWEE1 (Antibody to)
Alternative techniqueantibodies
Identity 12761
Gene WEE1
Long gene name WEE1 G2 checkpoint kinase
Synonyms gene name pombe) , pombe) homolog WEE1 homolog (S, wee1+ (S
Synonyms WEE1A
Locus 11p15, 4
Discovery year 1992-08-06
GenBank acession X62048
Entrez gene record 7465
Pubmed identfication 1840647
RefSeq identity NM_003390
Havana BLAST/BLAT OTTHUMG00000165863

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