Filters

Wee1(Ser123) Antibody

Wee1(Ser123) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameWee1(Ser123) Primary Polyclonal Antibody
Also known asWee1(Ser123) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenWee1 Ser123
Specificity Rat, The peptide used to produce this antibody has high homology with a sequence occurring in MIER3, This phosphorylation site is homologous to Ser123 in Mouse, and Bovine, and may react with this protein in Mouse and Human when phosphorylated at the site of Ser10, This is a highly specific antibody against Wee1 Ser123
Modification(s)Phosphorylation
Modification site(s)Ser123
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range100-150/646
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human Wee1 around the phosphorylation site of Ser123 [SS(p-S)PV]
Gene ID number7465
Swiss ProtP30291
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A correlated decrease in protein level occurs at M/G1 phase, Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated, Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur, Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase, probably due to its degradation, Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names WEE1, WEE1hu, Wee1-like protein kinase, Wee1A kinase, WEE1A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetWee1(Ser123)
Short nameWee1(Ser123) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameWee1(Ser123) (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter