Name : Wee1(Ser123) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN7509998360
| Long name | ALEXA FLUOR 555 Conjugated, Wee1(Ser123) Polyclonal Antibody |
| Also known as | Anti-Wee1 Ser123 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Wee1 Ser123 |
| Specificity | This is a highly specific antibody against Wee1 Ser123 |
| Modification | Phosphorylation |
| Modification Site | Ser123 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 100-150/646 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic phosphopeptide derived from human Wee1 around the phosphorylation site of Ser123 [SS(p-S)PV] |
| Gene ID Number | 7465 |
| Swiss Prot | P30291 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A correlated decrease in protein level occurs at M/G1 phase, Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated, Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur, Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase, probably due to its degradation, Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15' |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | WEE1, WEE1hu, Wee1-like protein kinase, Wee1A kinase, WEE1A |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | Wee1(Ser123) |
| Short name | Wee1(Ser123) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, Wee1(Ser123) (Antibody to) |
| Alternative technique | antibodies |