| Long name | WFS1 Primary Polyclonal Antibody |
| Also known as | WFS1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | WFS1 |
| Specificity | This is a highly specific antibody against WFS1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 780-830/890 |
| Subcellular location | Lumenal |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WFS1 |
| Gene ID number | 7466 |
| Swiss Prot | O76024 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store, Participates in the regulation of cellular Ca(2+) homeostasis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CTRCT41, WFRS, WFS1, WFSL, Wolframin, WFS |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | WFS1 |
| Short name | WFS1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Wolfram syndrome 1 (wolframin) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ATPase binding, CTRCT41 and WFRS and WFS and WFSL, Cytoplasm, WFS1 and IDBG-643358 and ENSBTAG00000046671 and 100298456, WFS1 and IDBG-8903 and ENSG00000109501 and 7466, Wfs1 and IDBG-158640 and ENSMUSG00000039474 and 22393, this GO :0001822 and kidney development and biological process this GO :0003091 and renal water homeostasis and biological process this GO :0005215 and transporter activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006983 and ER overload response and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0022417 and protein maturation by protein folding and biological process this GO :0030176 and integral component of endoplasmic reticulum membrane and cellular component this GO :0030425 and dendrite and cellular component this GO :0030433 and ER-associated ubiquitin-dependent protein catabolic process and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032469 and endoplasmic reticulum calcium ion homeostasis and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0042048 and olfactory behavior and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043069 and negative regulation of programmed cell death and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0045927 and positive regulation of growth and biological process this GO :0048306 and calcium-dependent protein binding and molecular function this GO :0050821 and protein stabilization and biological process this GO :0050877 and neurological system process and biological process this GO :0051117 and ATPase binding and molecular function this GO :0051247 and positive regulation of protein metabolic process and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0070845 and polyubiquitinated misfolded protein transport and biological process this GO :1902236 and negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :2000675 and negative regulation of type B pancreatic cell apoptotic process and biological process, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0005516: calmodulin binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0033613: activating transcription factor binding and also this GO :0048306: calcium-dependent protein binding and also this GO :0051117: ATPase binding, this GO :0005516: calmodulin binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0033613: activating transcription factor binding, this GO :0048306: calcium-dependent protein binding, this GO :0051117: ATPase binding, Wolfram syndrome 1 (wolframin) |
| Identity | 12762 |
| Gene | WFS1 |
| Long gene name | wolframin ER transmembrane glycoprotein |
| Synonyms gene | DFNA6 DFNA14 DFNA38 |
| Synonyms gene name | Wolfram syndrome 1 (wolframin) |
| Synonyms | DIDMOAD WFS |
| Locus | 4p16, 1 |
| Discovery year | 1995-01-30 |
| GenBank acession | AF084481 |
| Entrez gene record | 7466 |
| Pubmed identfication | 7987399 9771706 |
| Havana BLAST/BLAT | OTTHUMG00000090431 |
| Locus Specific Databases | Hereditary Hearing Loss Homepage |
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