Name : WISP3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8386267400
| Long name | WISP3 Primary Polyclonal Antibody |
| Also known as | WISP3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | WISP3 |
| Specificity | This is a highly specific antibody against WISP3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WISP3 |
| Gene ID number | 8838 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Both WISP-1 and WISP-2 are upregulated in cells transformed with the proto-oncogene Wnt-1, WISP-1, WISP-1 expression is observed in various tissues including adult heart, WISP-2 and WISP-3 are members of the CCN family of growth factors, WISP-2 and WISP-3 share significant sequence similarity, WISP-3 is involved in normal post-natal skeletal growth, and it is also implicated in the development of the autosomal recessive skeletal disorder progressive pseudorheumatoid dysplasia, and they are also more highly expressed in human colon tumors, and they are believed to function as dimers in their active forms, colon and ovary, including four conserved cysteine-rich domains, kidney and spleen, suggesting that these proteins may participate in tumor development, which affects cartilage homeostasis by disrupting the growth of chondrocyte and normal cell columnar organization, which include connective tissue growth factor (CTGF) and Cyr61, while WISP-2 expression predominates in skeletal muscle, Wnt-induced secreted protein (WISP)-1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CCN family member 6, CCN6, CYR61, LIBC, Lost in inflammatory breast cancer tumor suppressor protein, MGC125987, MGC125988, MGC125989, OTTHUMP00000040421, PPAC, PPD, UNQ462/PRO790/PRO956, WISP 3, WISP-3, WISP3, WISP3_HUMAN, WNT 1 inducible signaling pathway protein 3, WNT1 inducible signaling pathway protein 3, WNT1 inducible signaling pathway protein 3 precursor, WNT1-inducible-signaling pathway protein 3, Wnt 1 signaling pathway protein 3, CCN 6 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | WISP3 |
| Short name | WISP3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | WISP3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12771 |
| Gene | WISP3 |
| Long gene name | WNT1 inducible signaling pathway protein 3 |
| Synonyms | CCN6 |
| Locus | 6q21 |
| Discovery year | 1999-01-22 |
| GenBank acession | AF100781 |
| Entrez gene record | 8838 |
| Pubmed identfication | 9843955 |
| RefSeq identity | NM_003880 |
| Classification | CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT | OTTHUMG00000185101 |