| Long name | WNK1 Primary Polyclonal Antibody |
| Also known as | WNK1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | WNK1 |
| Specificity | This is a highly specific antibody against WNK1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WNK1 |
| Gene ID number | 65125 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | SLC12A3, WNK1 may also play a role in actin cytoskeletal reorganization, WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, by phosphorylation, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1, WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HSAN2, HSN2, KDP, KIAA0344, Kinase deficient protein, MGC163339, MGC163341, PRKWNK1, PSK, Prostate derived sterile 20 like kinase, Protein kinase lysine deficient 1, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, Serine/threonine protein kinase WNK1, Serine/threonine-protein kinase WNK1, WNK lysine deficient protein kinase 1, WNK1, WNK1_HUMAN, With no K, hWNK1, p65, Erythrocyte 65 kDa protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | WNK1 |
| Short name | WNK1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | WNK lysine deficient protein kinase 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, WNK1 and IDBG-11521 and ENSG00000060237 and 65125, WNK1 and IDBG-641017 and ENSBTAG00000005221 and 506433, Wnk1 and IDBG-183036 and ENSMUSG00000045962 and 232341, this GO :0003084 and positive regulation of systemic arterial blood pressure and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006811 and ion transport and biological process this GO :0010923 and negative regulation of phosphatase activity and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004860: protein kinase inhibitor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004860: protein kinase inhibitor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019869: chloride channel inhibitor activity, this GO :0019902: phosphatase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019869: chloride channel inhibitor activity and also this GO :0019902: phosphatase binding, transferring phosphorus-containing groups and molecular function this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019869 and chloride channel inhibitor activity and molecular function this GO :0019902 and phosphatase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0048666 and neuron development and biological process this GO :0050794 and regulation of cellular process and biological process this GO :0090188 and negative regulation of pancreatic juice secretion and biological process, WNK lysine deficient protein kinase 1 |
| Identity | 14540 |
| Gene | WNK1 |
| Long gene name | WNK lysine deficient protein kinase 1 |
| Synonyms gene | PRKWNK1 HSN2 |
| Synonyms gene name | lysine deficient 1 hereditary sensory neuropathy, protein kinase, type II |
| Synonyms | HSAN2 PPP1R167 |
| Synonyms name | protein phosphatase 1, regulatory subunit 167 |
| Locus | 12p13, 33 |
| Discovery year | 2001-02-06 |
| GenBank acession | AJ296290 |
| Entrez gene record | 65125 |
| RefSeq identity | NM_018979 |
| Classification | Minor histocompatibility antigens Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000090321 |
| Locus Specific Databases | Inherited Peripheral Neuropathies Mutation Database LRG_247 |
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