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WNK4 Antibody, Cy7 Conjugated

WNK4 Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, WNK4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenWNK4
SpecificityThis is a highly specific antibody against WNK4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human WNK4
Gene ID number65266
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also inhibits the renal K(+)channel, KCNJ1, SLC12A3, WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis, by phosphorylation which appears to prevent membrane trafficking of SLC12A3, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis, Regulates the activity of the thiazide-sensitive Na-Cl cotransporter
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetWNK4 Conjugated
Short name Conjugated, WNK4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, WNK lysine deficient protein kinase 4 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cell surfaces, WNK4 and IDBG-51675 and ENSG00000126562 and 102724304, WNK4 and IDBG-640438 and ENSBTAG00000019907 and 100849076, Wnk4 and IDBG-211994 and ENSMUSG00000035112 and 69847, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005923 and tight junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006811 and ion transport and biological process this GO :0006821 and chloride transport and biological process this GO :0008104 and protein localization and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019869: chloride channel inhibitor activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019869: chloride channel inhibitor activity, transferring phosphorus-containing groups and molecular function this GO :0019869 and chloride channel inhibitor activity and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0050794 and regulation of cellular process and biological process this GO :0050801 and ion homeostasis and biological process this GO :0070294 and renal sodium ion absorption and biological process this GO :0072156 and distal tubule morphogenesis and biological process this GO :0090188 and negative regulation of pancreatic juice secretion and biological process, 65266, WNK lysine deficient protein kinase 4
Identity 14544
Gene WNK4
Long gene name WNK lysine deficient protein kinase 4
Synonyms gene PRKWNK4
Synonyms gene name lysine deficient 4 , protein kinase
Locus 17q21, 2
Discovery year 2001-02-07
GenBank acession AJ309861
Entrez gene record 65266
Havana BLAST/BLAT OTTHUMG00000180650

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