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WWP1 Antibody

WWP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameWWP1 Primary Polyclonal Antibody
Also known asWWP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenWWP1
SpecificityThis is a highly specific antibody against WWP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WWP1
Gene ID number11059
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen SMAD4 and TGFbetaR1), The HECT domain of WWP1 has been implicated in regulating the localization and stability of p53 â, WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, WWP1 also negatively regulates the TGF beta tumor suppressor pathway by inactivating its molecular components (SMAD2, WWP1 contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain, WWP1 has been implicated in both breast and prostate cancers, and RNA splicing, inhibition of WWP1 results in a decrease in p53 expression, transcription, whilst WWP1 mediated stabilization of p53 appears to be associated with an accumulation of cytoplasmic p53, &euro, &ldquo, WWP1 is an E3 ubiquitin ligase and belongs to a family of NEDD4-like proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AIP5, Atropin-1-interacting protein 5, NEDD4-like E3 ubiquitin-protein ligase WWP1, Tiul1, WW domain containing E3 ubiquitin protein ligase 1, WW domain-containing protein 1, WWP 1, WWP1_HUMAN, hSDRP1, nedd4 like, AIP 5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetWWP1
Short nameWWP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameWW domain containing E3 ubiquitin protein ligase 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target AIP5 and hSDRP1 and Tiul1, DNA-templated and biological process this GO :0046718 and viral entry into host cell and biological process this GO :0055085 and transmembrane transport and biological process, WWP1 and IDBG-27568 and ENSG00000123124 and 11059, WWP1 and IDBG-645403 and ENSBTAG00000015720 and 513789, Wwp1 and IDBG-131115 and ENSMUSG00000041058 and 107568, ligase activity, nuclei, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007417 and central nervous system development and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0034220 and ion transmembrane transport and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0045892 and negative regulation of transcription, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0016874: ligase activity, this GO :0005515: protein binding, this GO :0016874: ligase activity, WW domain containing E3 ubiquitin protein ligase 1
Identity 17004
Gene WWP1
Long gene name WW domain containing E3 ubiquitin protein ligase 1
Synonyms AIP5 DKFZP434D2111
Locus 8q21, 3
Discovery year 2004-07-07
GenBank acession AY043361
Entrez gene record 11059
Pubmed identfication 9169421 9647693
RefSeq identity NM_007013
Classification C2 and WW domain containing
Havana BLAST/BLAT OTTHUMG00000163690

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