Name : XRCC4 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2025254931
| Long name | ALEXA FLUOR 594 Conjugated, XRCC4 Polyclonal Antibody |
| Also known as | Anti-XRCC4 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | XRCC4 |
| Specificity | This is a highly specific antibody against XRCC4 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 170-212/336 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human XRCC4 |
| Gene ID Number | 7518 |
| Swiss Prot | Q13426 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends, Binds to DNA and to DNA ligase IV (LIG4), The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4, Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | XRCC4 |
| Short name | XRCC4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, X-ray repair complementing defective repair in Chinese hamster cells 4 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | XRCC4 and IDBG-32219 and ENSG00000152422 and 7518, XRCC4 and IDBG-646520 and ENSBTAG00000024275 and 613590, Xrcc4 and IDBG-171005 and ENSMUSG00000021615 and 108138, nuclei, protein C-terminus binding, this GO :0001701 and in utero embryonic development and biological process this GO :0002328 and pro-B cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005958 and DNA-dependent protein kinase-DNA ligase 4 complex and cellular component this GO :0006266 and DNA ligation and biological process this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0007417 and central nervous system development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0010165 and response to X-ray and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0016032 and viral process and biological process this GO :0030054 and cell junction and cellular component this GO :0032807 and DNA ligase IV complex and cellular component this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033151 and V(D)J recombination and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045190 and isotype switching and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051103 and DNA ligation involved in DNA repair and biological process this GO :0051351 and positive regulation of ligase activity and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071285 and cellular response to lithium ion and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, X-ray repair complementing defective repair in Chinese hamster cells 4 |
| Identity | 12831 |
| Gene | XRCC4 |
| Long gene name | X-ray repair cross complementing 4 |
| Synonyms gene name | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| Synonyms name | X-ray repair, complementing defective, repair in Chinese hamster DNA repair protein XRCC4 |
| Locus | 5q14, 2 |
| Discovery year | 1990-10-16 |
| GenBank acession | AB017445 |
| Entrez gene record | 7518 |
| Pubmed identfication | 1697445 7665175 |
| RefSeq identity | NM_022550 |
| Havana BLAST/BLAT | OTTHUMG00000131319 |