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YB1 Antibody

YB1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameYB1 Primary Polyclonal Antibody
Also known asYB1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenYB1
SpecificityThis is a highly specific antibody against YB1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range120-170/324
Subcellular location Nucleus, Secreted, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human YBX-1
Gene ID number4904
Swiss ProtP67809
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds and stabilizes cytoplasmic mRNA, Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro, Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), Binds to splice sites in pre-mRNA and regulates splice site selection, Component of the CRD-mediated complex that promotes MYC mRNA stability, Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity), Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7', May play a role in DNA repair, Promotes separation of DNA strands that contain mismatches or are modified by cisplatin, Regulates the transcription of numerous genes, The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation, such as MDR1 and HLA class II genes, Mediates pre-mRNA alternative splicing regulation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BP-8, CBF-A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, DBPB, DNA-binding protein B, EFI-A, Enhancer factor I subunit A, MDR-NF1, NSEP-1, NSEP1, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, YB1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetYB1
Short nameYB1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameYB1 (Antibody to)
Alternative techniqueantibodies
Identity 8014
Gene YBX1
Long gene name Y-box binding protein 1
Synonyms gene NSEP1
Synonyms gene name nuclease sensitive element binding protein 1
Synonyms YB-1 YB1 DBPB NSEP-1 MDR-NF1 BP-8 CSDB CSDA2
Locus 1p34, 2
Discovery year 1993-10-20
GenBank acession BC013838
Entrez gene record 4904
Pubmed identfication 1891370 3174636
RefSeq identity NM_004559
Classification Y box binding proteins
Havana BLAST/BLAT OTTHUMG00000007523

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