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YB1 Antibody, Cy3 Conjugated

YB1 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, YB1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenYB1
SpecificityThis is a highly specific antibody against YB1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range120-170/324
Subcellular location Nucleus, Secreted, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human YBX-1
Gene ID number4904
Swiss ProtP67809
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds and stabilizes cytoplasmic mRNA, Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro, Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), Binds to splice sites in pre-mRNA and regulates splice site selection, Component of the CRD-mediated complex that promotes MYC mRNA stability, Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity), Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7', May play a role in DNA repair, Promotes separation of DNA strands that contain mismatches or are modified by cisplatin, Regulates the transcription of numerous genes, The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation, such as MDR1 and HLA class II genes, Mediates pre-mRNA alternative splicing regulation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms YB-1 YB1 DBPB NSEP-1 MDR-NF1 BP-8 CSDB CSDA2
Properties 1 of the YB1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetYB1 Conjugated
Short name Conjugated, YB1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, YB1 (Antibody to)
Alternative techniqueantibodies
Identity 8014
Gene YBX1
Long gene name Y-box binding protein 1
Synonyms gene NSEP1
Synonyms gene name nuclease sensitive element binding protein 1
Locus 1p34, 2
Discovery year 1993-10-20
GenBank acession BC013838
Entrez gene record 4904
Pubmed identfication 1891370 3174636
RefSeq identity NM_004559
Classification Y box binding proteins
Havana BLAST/BLAT OTTHUMG00000007523

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