Name : Yellow fever virus envelope glycoprotein E Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3193872196
| Long name | ALEXA FLUOR 488 Conjugated, Yellow fever virus envelope glycoprotein E Antibody |
| Also known as | Anti-Yellow fever virus envelope glycoprotein E PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Yellow fever virus envelope glycoprotein E |
| Specificity | This is a highly specific antibody against Yellow fever virus envelope glycoprotein E |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 650-700/3411 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from Yellow fever virus envelope glycoprotein E (IIVGRGDSRLTY) |
| Gene ID Number | 1502173 |
| Swiss Prot | P03314 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Virus |
| Cross-reactive species details | Yellow fever virus |
| Background of the antigen | After cleavage by host furin, After cleavage of prM, Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis, Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes, NS2A-NS2B, NS2B-NS3, NS3 RNA helicase binds RNA and unwinds dsRNA in the 3' to 5' direction (By similarity), NS3 serine protease, NS3-NS4A, NS4A-2K and NS4B-NS5, NTPase and RNA helicase, Non-structural protein 1 is involved in virus replication and regulation of the innate immune response, Non-structural protein 2A may be involved viral RNA replication and capsid assembly, Non-structural protein 2B is a required cofactor for the serine protease function of NS3, Non-structural protein 4A induces host endoplasmic reticulum membrane rearrangements leading to the formation of virus-induced membranous vesicles hosting the dsRNA and polymerase, Serine protease NS3 displays three enzymatic activities: serine protease, Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E, The capsid encapsulates the genomic RNA (By similarity), envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity), functioning as a replication complex, in association with NS2B, performs its autocleavage and cleaves the polyprotein at dibasic sites in the cytoplasm: C-prM, prM acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide, prM is matured in the last step of virion assembly, presumably to avoid catastrophic activation of the viral fusion peptide induced by the acidic pH of the trans-Golgi network, the pr peptide is released in the extracellular medium and small envelope protein M and envelope protein E homodimers are dissociated (By similarity), Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | Genome polyprotein |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the fever virus envelope glycoprotein E Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | fever virus envelope glycoprotein E |
| Short name | fever virus envelope glycoprotein E Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Yellow fever virus envelope glycoprotein E (Antibody to) |
| Alternative technique | antibodies |