YES1 (1612CT505.7.50) Monoclonal Antibody

YES1 (1612CT505.7.50) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

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Long name	50) Monoclonal Antibody, 7, YES1 (1612CT505
Also known as	50) Monoclonal Antibody, 7, YES1 (1612CT505
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	YES1
Specificity	This is a highly specific antibody against YES1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	1612CT505, 7, 50
Source	This YES1 antibody is generated from a mouse immunized with a recombinant protein of human YES1
Gene ID number	7525
Swiss Prot	P07947
Tested Applications	WB
Recommended dilutions	WB(1:4000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Also involved in G2/M progression and cytokinesis, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, PDGFR, Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration, Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts, Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase, Stimulation by receptor tyrosine kinases (RTKs) including EGRF, Upon EGFR activation, Upon T-cell stimulation by CXCL12, and activation and phosphorylation of downstream substrates, and differentiation, apoptosis, cell-cell adhesion, cytoskeleton remodeling, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly, Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	HsT441, P61-YES, Proto-oncogene c-Yes, Tyrosine-protein kinase Yes, YES1, c-yes, Yes
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	50) Monoclonal, 7, YES1 (1612CT505
Short name	50) Monoclonal Antibody, 7, YES1 (1612CT505
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	50) monoclonal (Antibody to), 7, YES1 (1612CT505
Alternative technique	antibodies
Identity	12841
Gene	YES1
Long gene name	Src family tyrosine kinase , YES proto-oncogene 1
Synonyms gene name	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Synonyms	Yes c-yes HsT441
Locus	18p11, 32
Discovery year	1986-01-01
GenBank acession	M15990
Entrez gene record	7525
Pubmed identfication	2983418
RefSeq identity	NM_005433
Classification	SH2 domain containing Src family tyrosine kinases
Havana BLAST/BLAT	OTTHUMG00000131472

YES1 (1612CT505.7.50) Monoclonal Antibody

YES1 (1612CT505.7.50) Monoclonal Antibody size: 0.1ml 281

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