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YES1 Antibody, Cy5.5 Conjugated

YES1 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, YES1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenYES1
Specificity Due to the high homology of this protein with Tyrosine-protein kinase Lck and Tyrosine-protein kinase Fyn, based upon sequence similarity, there is a chance that this antibody will cross-react with these proteins, This is a highly specific antibody against YES1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range480-530/541
Subcellular location Cell membrane, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human YES1
Gene ID number7525
Swiss ProtP07947
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also involved in G2/M progression and cytokinesis, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, PDGFR, Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration, Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts, Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase, Stimulation by receptor tyrosine kinases (RTKs) including EGRF, Upon EGFR activation, Upon T-cell stimulation by CXCL12, and activation and phosphorylation of downstream substrates, and differentiation, apoptosis, cell-cell adhesion, cytoskeleton remodeling, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly, Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms Yes c-yes HsT441
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetYES1 Conjugated
Short name Conjugated, YES1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, YES1 (Antibody to)
Alternative techniqueantibodies
Identity 12841
Gene YES1
Long gene name Src family tyrosine kinase , YES proto-oncogene 1
Synonyms gene name v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Locus 18p11, 32
Discovery year 1986-01-01
GenBank acession M15990
Entrez gene record 7525
Pubmed identfication 2983418
RefSeq identity NM_005433
Classification SH2 domain containing Src family tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000131472

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