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YKL39/CHI3L2 Antibody, Cy7 Conjugated

YKL39/CHI3L2 Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, YKL39/CHI3L2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenYKL39/CHI3L2
SpecificityThis is a highly specific antibody against YKL39/CHI3L2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human YKL39/CHI3L2
Gene ID number7690
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additionally, Although related to bacterial chitinases, Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, YKL-39 binds glycan structures with high affinity, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions, YKL-39 lacks the characteristic glutamate active site and, does not have enzymatic chitinase activity, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease, thus, YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms YKL-39 YKL39
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetYKL39/CHI3L2 Conjugated
Short name Conjugated, YKL39/CHI3L2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, YKL39/CHI3L2 (Antibody to)
Alternative techniqueantibodies
Identity 1933
Gene CHI3L2
Long gene name chitinase 3 like 2
Synonyms gene name chitinase 3-like 2
Locus 1p13, 2
Discovery year 1994-12-20
GenBank acession U49835
Entrez gene record 1117
Pubmed identfication 8702629
RefSeq identity NM_004000
Classification Chitinases
Havana BLAST/BLAT OTTHUMG00000012174

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