Name : ZFYVE27 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9974345932
| Long name | ALEXA FLUOR 488 Conjugated, ZFYVE27 Polyclonal Antibody |
| Also known as | Anti-ZFYVE27 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ZFYVE27 |
| Specificity | This is a highly specific antibody against ZFYVE27 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZFYVE27 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Five isoforms of ZFYVE27 exist as a result of alternative splicing events, Mutations in the gene encoding ZFTVE27 affect neuronal intracellular trafficking in the corticospinal tract and are thought to lead to hereditary spastic paraplegia (HSP), The FYVE domain is a cysteine-rich domain of about 70 amino acids that plays a role in the endosomal localization of the FYVE-finger proteins, ZFYVE27, a multi-pass membrane protein, a neurodegenerative disorder, a protein that is primarily involved in microtubule dynamics and severing, also known as SPG33, and a majority of these proteins serve as regulators of endocytic membrane trafficking, characterized by progressive paralysis of the legs, is a 411 amino acid member of the FYVE-finger family of proteins, is an endosomal protein that binds to Spastin, vesicular trafficking and endosomal trafficking, which is caused by impaired axonal transport, Zinc finger FYVE domain-containing protein 27 (ZFYVE27) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FLJ32919 SPG33 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ZFYVE27 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | ZFYVE27 |
| Short name | ZFYVE27 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, ZFYVE27 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26559 |
| Gene | ZFYVE27 |
| Long gene name | zinc finger FYVE-type containing 27 |
| Synonyms gene name | FYVE domain containing 27 , zinc finger |
| Synonyms name | protrudin |
| Locus | 10q24, 2 |
| Discovery year | 2004-03-05 |
| GenBank acession | BC030621 |
| Entrez gene record | 118813 |
| Pubmed identfication | 14702039 |
| RefSeq identity | NM_144588 |
| Classification | Zinc fingers FYVE-type |
| Havana BLAST/BLAT | OTTHUMG00000018867 |