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ZFYVE27 Antibody, FITC Conjugated

ZFYVE27 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, ZFYVE27 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenZFYVE27
SpecificityThis is a highly specific antibody against ZFYVE27
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ZFYVE27
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Five isoforms of ZFYVE27 exist as a result of alternative splicing events, Mutations in the gene encoding ZFTVE27 affect neuronal intracellular trafficking in the corticospinal tract and are thought to lead to hereditary spastic paraplegia (HSP), The FYVE domain is a cysteine-rich domain of about 70 amino acids that plays a role in the endosomal localization of the FYVE-finger proteins, ZFYVE27, a multi-pass membrane protein, a neurodegenerative disorder, a protein that is primarily involved in microtubule dynamics and severing, also known as SPG33, and a majority of these proteins serve as regulators of endocytic membrane trafficking, characterized by progressive paralysis of the legs, is a 411 amino acid member of the FYVE-finger family of proteins, is an endosomal protein that binds to Spastin, vesicular trafficking and endosomal trafficking, which is caused by impaired axonal transport, Zinc finger FYVE domain-containing protein 27 (ZFYVE27)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ32919 SPG33
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetZFYVE27 Conjugated
Short name FITC Conjugated, ZFYVE27 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, ZFYVE27 (Antibody to)
Alternative techniqueantibodies
Identity 26559
Gene ZFYVE27
Long gene name zinc finger FYVE-type containing 27
Synonyms gene name FYVE domain containing 27 , zinc finger
Synonyms name protrudin
Locus 10q24, 2
Discovery year 2004-03-05
GenBank acession BC030621
Entrez gene record 118813
Pubmed identfication 14702039
RefSeq identity NM_144588
Classification Zinc fingers FYVE-type
Havana BLAST/BLAT OTTHUMG00000018867

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