Name : ZNF148/ZBP-89 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2666410829
| Long name | ZNF148/ZBP-89 Primary Polyclonal Antibody |
| Also known as | ZNF148/ZBP-89 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ZNF148/ZBP-89 |
| Specificity | This is a highly specific antibody against ZNF148/ZBP-89 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZNF148/ZBP-89 |
| Gene ID number | 7707 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Elevated levels of ZBP-89 induce growth arrest and apoptosis in human gastrointestinal cells, ZBP-89, ZBP-89 also regulates cell proliferation, ZBP-89 cooperates with histone acetyltransferase coactivator p300 in the regulation of p21, ZBP-89 expression is induced by trans-retinoic acid or butyrate, ZBP-89 has been shown to bind to GC-rich DNA elements in promoters for gastrin, a Kruppel-like repressor protein, a cyclin-dependent kinase inhibitor whose associated gene is a target gene of p53, in part, is the silencer element binding factor for Vimentin, ornithine decarboxylase and the cyclin-dependent kinase inhibitor p21 (also designated Cip1 or WAF1), through its ability to directly bind the p53 protein and retard its nuclear export, which also induces terminal differentiation of colon cancer cells, ZNF148 is a zinc finger transcription factor that is universally expressed |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Transcription factor ZBP89, ZBP89, ZN148_HUMAN, ZNF 148, ZNF148, Zinc finger DNA binding protein 89, Zinc finger DNA-binding protein 89, Zinc finger protein 148, Transcription factor ZBP-89 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ZNF148/ZBP-89 |
| Short name | ZNF148/ZBP-89 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | zinc finger protein 148/ZBP-89 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BERF-1 and BFCOL1 and HT-BETA and pHZ-52 and ZBP-89 and ZFP148, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function, ZNF148 and IDBG-54018 and ENSG00000163848 and 7707, ZNF148 and IDBG-633628 and ENSBTAG00000040031 and 613265, Zfp148 and IDBG-155354 and ENSMUSG00000022811 and 22661, metal ion binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006968 and cellular defense response and biological process this GO :0007276 and gamete generation and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0021762 and substantia nigra development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, this GO :0000976: transcription regulatory region sequence-specific DNA binding, this GO :0000976: transcription regulatory region sequence-specific DNA binding and also this GO :0003676: nucleic acid binding and also this GO :0003677: DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046872: metal ion binding, this GO :0003676: nucleic acid binding, this GO :0003677: DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, this GO :0046872: metal ion binding, zinc finger protein 148 |
| Identity | 12933 |
| Gene | ZNF148 |
| Long gene name | zinc finger protein 148 |
| Synonyms gene name | zinc finger protein 148 (pHZ-52) |
| Synonyms | BERF-1 ZBP-89 BFCOL1 HT-BETA ZFP148 pHZ-52 |
| Locus | 3q21, 2 |
| Discovery year | 1994-03-16 |
| GenBank acession | U09851 |
| Entrez gene record | 7707 |
| Pubmed identfication | 7557990 9925940 |
| RefSeq identity | NM_021964 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000159448 |