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ZNRF2 Antibody, Biotin Conjugated

ZNRF2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ZNRF2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenZNRF2
SpecificityThis is a highly specific antibody against ZNRF2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ZNRF2
Gene ID number223082
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Expressed at high levels in brain tissue, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), Upon DNA damage, ZNRF2 (zinc and ring finger 2), ZNRF2 is subject to phosphorylation, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity, also known as RNF202, as well as the endosome and the cell junction, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, probably by ATR or ATM, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms RNF202
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetZNRF2 Conjugated
Short name Conjugated, ZNRF2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ZNRF2 (Antibody to)
Alternative techniqueantibodies
Identity 22316
Gene ZNRF2
Long gene name zinc and ring finger 2
Synonyms gene name E3 ubiquitin protein ligase , zinc and ring finger 2
Locus 7p14, 3
Discovery year 2004-07-29
GenBank acession AF513707
Entrez gene record 223082
Pubmed identfication 22797923
RefSeq identity NM_147128
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000097759

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