Filters

ZO-3 Antibody

ZO-3 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenZO-3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the ZO-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis ZO-3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O95049
PurityAntigen affinity
Description 1999), Haskins et al, In vitro studies showed that the sixth and eighth PDZ domains of PATJ mediated interaction with the Tjp3 C-terminal domain and with Cldn1, It is a member of the family of membrane-associated guanylate kinase-like proteins (MAGUK) that associate with intracellular junctions (Itoh et al, Roh et al, also called ZO-3 (Zona occludens 3), is a protein that in humans is encoded by the TJP3 gene, respectively, (1998) showed that recombinant Tjp3 binds in vitro translated Tjp1 and binds directly to the cytoplasmic tail of occludin but no binding was detected between Tjp3 and Tjp2, (2002) determined that Tjp3 interacted with PATJ(INADL) and that both proteins colocalized to tight junctions in vivo, TJP3 (Tight junction protein 3)
ImmunogenAn amino acid sequence from the C-terminus of human Zonula occludens protein 3 (RVHDAESSDEDGYDWGPATDL) was used as the immunogen for this ZO-3 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ZO-3 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetZO-3
Short nameZO-3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameZO-3 (Antibody to)
Alternative techniqueantibodies
Identity 11829
Gene TJP3
Long gene name tight junction protein 3
Synonyms ZO-3
Synonyms name zona occludens 3
Locus 19p13, 3
Discovery year 2000-02-16
GenBank acession AC005954
Entrez gene record 27134
Classification Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000180872

Similar products

Subscribe to our Newsletter