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ZW10 peptide Antibody, ALEXA FLUOR 488

ZW10 peptide Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, ZW10 peptide Polyclonal Antibody
Also known asAnti-ZW10 peptide PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenZW10 peptide
SpecificityThis is a highly specific antibody against ZW10 peptide
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse ZW10
Gene ID Number9183
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores, In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, It is part of the MIS12 complex, The encoded protein binds to centromeres during the prophase, This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division, Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyze generation of the mitotic checkpoint-derived ", Zwint-1, Zwint-1 is critical for recruiting ZW10 to unattached kinetochores, and early anaphase cell division stages and to kinetochore microtubules during metaphase, inhibitor, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1, metaphase, whereas another ZW10 partner, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis, The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors, stop anaphase"
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms KNTC1AP
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ZW10 peptide Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description , The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs, The shortest peptides are dipeptides, These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), and unbranched synthetic peptide chains, consisting of 2 amino acids joined by a single peptide bond, continuous, followed by tripeptides, or in continue produced for custom peptide synthesis projects, tetra peptides, till polypeptides that are long, Peptides short amino acid chains or epitopes or blocking antagonists
Gene targetZW10 peptide
Short nameZW10 peptide Antibody
Technique antibodies against human proteins, antibodies for, peptides, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ZW10 short protein sequence (Antibody to)
Alternative techniqueantibodies
Identity 13194
Gene ZW10
Long gene name zw10 kinetochore protein
Synonyms gene name ZW10 (Drosophila) homolog, centromere/kinetochore protein ZW10, homolog (Drosophila) , kinetochore associated
Locus 11q23, 2
Discovery year 1999-05-11
GenBank acession U54996
Entrez gene record 9183
Pubmed identfication 9298984
RefSeq identity NM_004724
Havana BLAST/BLAT OTTHUMG00000168190

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