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ZWILCH Antibody

ZWILCH Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameZWILCH Primary Polyclonal Antibody
Also known asZWILCH PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenZWILCH
SpecificityThis is a highly specific antibody against ZWILCH
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZWILCH
Gene ID number55055
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Mutations were discovered in Zwilch, The Drosophila Zwilch forms a complex with both ROD Rough Deal) and ZWINT (Zeste-White 10, The human Zwilch, The role of Zwilch in complex is thought to be evolutionarily conserved because the human homologs of Zwilch, These mutations may contribute in part to the chromosomal instability phenotype of colorectal tumor cells, This complex is important for chromosome segregation because it recruits cytoplasmic Dynein to the kinetochore and plays a crucial role in the spindle checkpoint, ZWINT and ROD coimmunoprecipitate in a human cell line called HeLa, ZWINT and ROD complex localizes to the kinetochores at prometaphase, ZWINT and ROD during a screen for mutations in alleles encoding putative chromosome instability genes in cases of human colorectal cancer, also designated ZW10) proteins, Zwilch is the human homolog of the Drosophila Zwilch protein
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KNTC1AP, MGC111034, Protein zwilch homolog, ZWILC_HUMAN, Zwilch, homolog, kinetochore associated, zwilch, hZwilch, y ZWILCH protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetZWILCH
Short nameZWILCH Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name homolog (Drosophila) (Antibody to), kinetochore associated, Zwilch
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, ZWILCH and IDBG-18211 and ENSG00000174442 and 55055, ZWILCH and IDBG-645460 and ENSBTAG00000005213 and 534811, Zwilch and IDBG-175909 and ENSMUSG00000032400 and 68014, homolog (Drosophila), kinetochore associated, protein binding, this GO :0000278 and mitotic cell cycle and biological process this GO :0000776 and kinetochore and cellular component this GO :0000777 and condensed chromosome kinetochore and cellular component this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0007067 and mitotic nuclear division and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, Zwilch
Identity 25468
Gene ZWILCH
Long gene name zwilch kinetochore protein
Synonyms gene name Zwilch, homolog (Drosophila) , kinetochore associated
Synonyms FLJ10036 KNTC1AP
Locus 15q22, 31
Discovery year 2005-07-25
GenBank acession AK023175
Entrez gene record 55055
Pubmed identfication 12686595
RefSeq identity NM_017975
Havana BLAST/BLAT OTTHUMG00000133194

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