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ZWILCH Antibody, Cy5 Conjugated

ZWILCH Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, ZWILCH Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenZWILCH
SpecificityThis is a highly specific antibody against ZWILCH
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ZWILCH
Gene ID number55055
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Mutations were discovered in Zwilch, The Drosophila Zwilch forms a complex with both ROD Rough Deal) and ZWINT (Zeste-White 10, The human Zwilch, The role of Zwilch in complex is thought to be evolutionarily conserved because the human homologs of Zwilch, These mutations may contribute in part to the chromosomal instability phenotype of colorectal tumor cells, This complex is important for chromosome segregation because it recruits cytoplasmic Dynein to the kinetochore and plays a crucial role in the spindle checkpoint, ZWINT and ROD coimmunoprecipitate in a human cell line called HeLa, ZWINT and ROD complex localizes to the kinetochores at prometaphase, ZWINT and ROD during a screen for mutations in alleles encoding putative chromosome instability genes in cases of human colorectal cancer, also designated ZW10) proteins, Zwilch is the human homolog of the Drosophila Zwilch protein
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms FLJ10036 KNTC1AP
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetZWILCH Conjugated
Short name Conjugated, ZWILCH Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, homolog (Drosophila) (Antibody to), kinetochore associated, Zwilch
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, ZWILCH and IDBG-18211 and ENSG00000174442 and 55055, ZWILCH and IDBG-645460 and ENSBTAG00000005213 and 534811, Zwilch and IDBG-175909 and ENSMUSG00000032400 and 68014, homolog (Drosophila), kinetochore associated, protein binding, this GO :0000278 and mitotic cell cycle and biological process this GO :0000776 and kinetochore and cellular component this GO :0000777 and condensed chromosome kinetochore and cellular component this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0007067 and mitotic nuclear division and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, Zwilch
Identity 25468
Gene ZWILCH
Long gene name zwilch kinetochore protein
Synonyms gene name Zwilch, homolog (Drosophila) , kinetochore associated
Locus 15q22, 31
Discovery year 2005-07-25
GenBank acession AK023175
Entrez gene record 55055
Pubmed identfication 12686595
RefSeq identity NM_017975
Havana BLAST/BLAT OTTHUMG00000133194

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