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ABCA4 Antibody

ABCA4 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenABCA4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the ABCA4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis ABCA4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P78363
PurityAntigen affinity
Description Allikmets et al, Allikmets et al, It is a member of the ATP-binding cassette transporter gene sub-family A(ABC1) found exclusively in multicellular eukaryotes, Member 4, Molday et al, Subfamily A, The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCA4-mediated foveal cone degeneration, Using a whole genome radiation hybrid panel, also known as ABCR, as well as rod, indicating that ABCA4 mediates the transport of an essential molecule(or ion) either into or out of photoreceptor cells, is a protein which in humans is encoded by the ABCA4 gene, photoreceptors, (1997) localized transcripts exclusively within photoreceptor cells, (1997) mapped the gene to 1p21-p13, (2000) showed by immunofluorescence microscopy and Western blot analysis that ABCA4 is present in foveal and peripheral cone, ATP-Binding Cassette
Immunogen Member 4 (TLLVQRHFFLSQWI) was used as the immunogen for this ABCA4 antibody, Subfamily A, An amino acid sequence from the C-terminus of human ATP-Binding Cassette
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ABCA4 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetABCA4
Short nameABCA4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameABCA4 (Antibody to)
Alternative techniqueantibodies
Identity 34
Gene ABCA4
Long gene name ATP binding cassette subfamily A member 4
Synonyms gene STGD1 ABCR RP19 STGD
Synonyms gene name ATP-binding cassette transporter, member 4 , retinal-specific ATP-binding cassette, sub-family A (ABC1)
Synonyms FFM ARMD2 CORD3
Synonyms name Stargardt disease
Locus 1p22, 1
Discovery year 1994-07-14
GenBank acession U88667
Entrez gene record 24
Pubmed identfication 9490294
RefSeq identity NM_000350
Classification ATP binding cassette subfamily A
Havana BLAST/BLAT OTTHUMG00000010622
Locus Specific Databases Mutations of the ATP-binding Cassette Transporter Retina

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