Name : ABCB4 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN9666065721
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | ABCB4 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the ABCB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This ABCB4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P21439 |
| Purity | Purified |
| Description | ABC genes are divided into seven distinct subfamilies (ABC1, ABC proteins transport various molecules across extra- and intra-cellular membranes, ALD, Alternative splicing of this gene results in several products of undetermined function, GCN20, MDR/TAP, MRP, Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation, OABP, The function of this protein has not yet been determined, This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate, This protein is a member of the MDR/TAP subfamily, White), however, it may involve transport of phospholipids from liver hepatocytes into bile, The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters |
| Immunogen | A portion of amino acids 624-654 from the human protein was used as the immunogen for this ABCB4 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ABCB4 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | ABCB4 |
| Short name | ABCB4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ABCB4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 45 |
| Gene | ABCB4 |
| Long gene name | ATP binding cassette subfamily B member 4 |
| Synonyms gene | PGY3 MDR3 |
| Synonyms gene name | ATP-binding cassette, member 4 , sub-family B (MDR/TAP) |
| Synonyms | MDR2 PFIC-3 GBD1 |
| Locus | 7q21, 12 |
| Discovery year | 1988-05-11 |
| GenBank acession | M23234 |
| Entrez gene record | 5244 |
| Pubmed identfication | 2892668 11313316 |
| RefSeq identity | NM_000443 |
| Classification | ATP binding cassette subfamily B |
| Havana BLAST/BLAT | OTTHUMG00000023396 |