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ACTH

ACTH size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asACTH
Other names Corticotropin-lipotropinCleaved into the following 11 chains:NPP, Melanotropin gammaAlternative name(s):Gamma-MSH, Pro-opiomelanocortin, adrenocorticotropic hormone, adrenocorticotropin, alpha-MSH, alpha-melanocyte-stimulating hormone, beta-LPH, beta-MSH, beta-endorphin, beta-melanocyte-stimulating hormone, corticotropin-like intermediary peptide, corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, opiomelanocortin prepropeptide, pro-ACTH-endorphin, pro-opiomelanocortin, proopiomelanocortin, proopiomelanocortin preproprotein, pro-opiomelanocortin preproprotein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene namePOMC
Gene name synonimsN/A
Other gene names ACTH, ACTH, CLIP, CLIP, LPH, MSH, NPP, POC, POMC, POMC, POMC
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
Clone57
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, Expected to show a broad species reactivity, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity ACTH, ACTH is also produced by cells of immune system (T-cells, Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease, B-cells, CLIP (corticotropin-like intermediary peptide), It also may react with other tumors (e, It reacts with ACTH-producing cells (corticotrophs), Lipotropin-beta, Lipotropin-gamma, POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, POMC is cleaved into ten hormone chains named NPP, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This MAb is specific to Synacthen (aa1-24 of ACTH), This particular antibody might cross react with speacies outside of the listed ones, alpha-MSH (Melanocyte Stimulating Hormone), and macrophages) in response to stimuli associated with stress, beta-MSH, beta-endorphin and Met-enkephalin, does not react with CLIP (aa17-39 of ACTH), gamma-MSH, some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH, tissue-specific posttranslational processing by convertases, ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary, g
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
Description or corticotrophins, Adrenocorticotropic hormone (ACTH)
Gene targetACTH
Short nameACTH
Alternative nameACTH
Identity 9201
Gene POMC
Long gene name proopiomelanocortin
Synonyms MSH POC CLIP ACTH NPP LPH
Synonyms name adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin adrenocorticotropic hormone opiomelanocortin prepropeptide
Locus 2p23, 3
Discovery year 1986-01-01
Entrez gene record 5443
Pubmed identfication 6254047 9620771
RefSeq identity NM_001035256
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000094764

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