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ACVR2A Antibody

ACVR2A Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenACVR2A
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis ACVR2A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P27037
PurityAntigen affinity
Description ACVR2A is an activin type 2 receptor, Alternative splicing results in multiple transcript variants of this gene, The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner, The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, This gene encodes a receptor that mediates the functions of activins, This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality, a transmembrane domain and a cytoplasmic serine-threonine kinase domain, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes, Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene
ImmunogenAmino acids Q421-L513 from the human protein were used as the immunogen for the ACVR2A antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ACVR2A antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization membranous, Cytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetACVR2A
Short nameACVR2A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameACVR2A (Antibody to)
Alternative techniqueantibodies
Identity 173
Gene ACVR2A
Long gene name activin A receptor type 2A
Synonyms gene ACVR2
Synonyms gene name activin A receptor, type II activin A receptor, type IIA
Synonyms ACTRII
Locus 2q22, 1 , 3-q23
Discovery year 1993-09-17
Entrez gene record 92
Pubmed identfication 1314589 10702675
RefSeq identity NM_001616
Classification Type 2 receptor serine/threonine kinases
Havana BLAST/BLAT OTTHUMG00000150603

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