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ADAM11 Antibody

ADAM11 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameADAM11 Primary Polyclonal Antibody
Also known asADAM11 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenADAM11
SpecificityThis is a highly specific antibody against ADAM11
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAM11
Gene ID number4185
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), ADAM11 null mutant mice have deficits in spatial learning and motor coordination, ADAM11 was mapped to 17q21, Another group identified ADAM11 in the human brain, EGF-like domain, Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, The domain structure of the full-length ADAM11 includes a signal sequence, The message was found only in the brain in this publication, Two splice variants with different carboxyterminal ends were described, a human embryonic carcinoma cell line, a region of interest for breast cancer, a spacer region, although they did have normal cell migration and differentiation during development, and mutations in ADAM11 are associated with some breast cancers, but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site, cys-rich domain, disintegrin-like domain, in search of brain-specific proteins, metalloproteinase-like domain, propeptide domain, then the transmembrane domain and a short cytoplasmic domain, where ADAM11 was thought to be involved in cell migration and spatial patterning, 3, ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ADA11_HUMAN, MDC, Metalloproteinase like, and cysteine rich protein, disintegrin like, A disintegrin and metalloproteinase domain 11
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetADAM11
Short nameADAM11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameADAM metallopeptidase domain 11 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ADAM11 and IDBG-54231 and ENSG00000073670 and 4185, ADAM11 and IDBG-640987 and ENSBTAG00000001735 and 522375, Adam11 and IDBG-212766 and ENSMUSG00000020926 and 11488, Extracellular, MDC, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0031012 and extracellular matrix and cellular component, this GO :0004222: metalloendopeptidase activity, this GO :0004222: metalloendopeptidase activity and also this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding, this GO :0005178: integrin binding, this GO :0005515: protein binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, zinc ion binding, ADAM metallopeptidase domain 11
Identity 189
Gene ADAM11
Long gene name ADAM metallopeptidase domain 11
Synonyms gene MDC
Synonyms gene name a disintegrin and metalloproteinase domain 11
Synonyms name cysteine-rich protein , disintegrin-like, metalloproteinase-like
Locus 17q21, 31
Discovery year 1993-11-01
GenBank acession D17390
Entrez gene record 4185
Pubmed identfication 8252040
RefSeq identity NM_002390
Classification ADAM metallopeptidase domain containing
Havana BLAST/BLAT OTTHUMG00000179038

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