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ADAM13 Antibody, Cy7 Conjugated

ADAM13 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, ADAM13 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenADAM13
SpecificityThis is a highly specific antibody against ADAM13
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from Xenopus laevis ADAM13
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityOther Species
Crossreactive species detailsXenopus laevis
Antigen background A member of the metalloproteinase family containing disintegrin like domains (ADAMs) the functions of ADAM13 are still poorly understood, ADAM13 contains a putative furin cleavage site, ADAM13 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, ADAM13 has been shown to be proteolytically active, ADAM13 is also shed from cells in culture, ADAM13 may also act as a cell attachment molecule, ADAM13 may regulate cellular signaling via Src and Src tyrosine kinase, ADAM13 was also found in liver, EFG like, It is still unclear if any of these ADAMs are species orthologs of Xenopus ADAM13, Predicted mass is 99, Shed ADAM13 is a 52 kD protein, The full length Xenopus ADAM13 sequence codes for a 914 amino acid protein, Xenopus ADAM13 has greatest homology with human ADAM 33 (51% identical), and 97 kD processed forms, and can form complexes with a2 macroglobulin, and intestines from adult Xenopus, and is 46% identical with human or mouse ADAM12 or ADAM19, and is released into the culture media, as well as disintegrin, but glycosylation and cyteine rich regions give Xenopus ADAM13 an apparent MW of 120 kD unprocessed, but there are significant differences between the related sequences, by binding integrins through the cysteine rich domain amoung many other roles, cleaved aminoterminal from the transmembrane domain, cleaving fibronectin after binding it to the EGF like domain, cysteine rich, heart, in developing Xenopus embryos, on reduced SDS PAGE gels, suggesting it is a competent protease, suggesting that ADAM13 may be a unique protein, suggesting that a prohormone convertase cleaves the propeptide domain away from the catalytic domain, transmembrane and Cytoplasmic domains, 749 kD, ADAM13 was first described as a protein expressed in somatic mesoderm and neural crest cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
SynonymsNULL
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetADAM13 Conjugated
Short name Conjugated, ADAM13 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, ADAM13 (Antibody to)
Alternative techniqueantibodies

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