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ADAM20 Antibody

ADAM20 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameADAM20 Primary Polyclonal Antibody
Also known asADAM20 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenADAM20
SpecificityThis is a highly specific antibody against ADAM20
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAM20
Gene ID number8748
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2), A member of the metalloproteinase family containing disintegrin-like domains (ADAMs) the function of ADAM20 is still poorly understood, ADAM17) have been more thoroughly studied, ADAM20 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, ADAM20 does not appear to contain a furin cleavage site, ADAM20 is closely related to ADAM21 (61% identical), ADAM20 message was seen predominantly in testis, ADAM29 (52% identical), Later, Other ADAMs family members (ADAM10, The full length ADAM20 sequence codes for a 726 amino acid protein, The sequence containing a Type-I transmembrane domain, Unlike many of the other ADAMs proteases, a full-length ADAM21 sequence demonstrated a functional catalytic domain, and a short cytoplasmic domain, and a wide range of other functions, and are known to play key roles in inflammation, and the initial partial sequence of ADAM21 contained a non-functional catalytic site, and the testases (49-46% identical), but also at lower levels in placenta and B-cells, but it may still be that the catalytically dead form of ADAM21 is expressed and functions as a fettilin, cystein-rich domain, growth factor maturation and release, making it tempting to speculate that ADAM20 and ADAM21 are orthologs to ADAMs 1&, metalloproteinase domain, with a predicted mass is 81, 2, 711 kD, ADAM20 was first cloned from a human testis library as a protein with homology to the fertilins (ADAMs 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names A disintegrin and metalloproteinase domain 20 preproprotein, ADA20_HUMAN, ADAM 20, ADAM metallopeptidase domain 20, ADAM20, Disintegrin and metalloproteinase domain-containing protein 20, EC 3, OTTHUMP00000236151, 4, 24, A disintegrin and metalloproteinase domain 20
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetADAM20
Short nameADAM20 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameADAM20 (Antibody to)
Alternative techniqueantibodies
Identity 199
Gene ADAM20
Long gene name ADAM metallopeptidase domain 20
Synonyms gene name a disintegrin and metalloproteinase domain 20
Locus 14q24, 2
Discovery year 1998-12-01
GenBank acession AF029899
Entrez gene record 8748
Pubmed identfication 9469942
Classification ADAM metallopeptidase domain containing
Havana BLAST/BLAT OTTHUMG00000167548

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