Filters

Adenomatous Polyposis Coli Antibody

Adenomatous Polyposis Coli Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAdenomatous Polyposis Coli Antibody
Also known asAdenomatous Polyposis Coli Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAPC/Adenomatous Polyposis Coli
SpecificityThis is a highly specific antibody against APC/Adenomatous Polyposis Coli
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range2790-2843/2843
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC
Gene ID number324
Swiss ProtP25054
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen APC activity is correlated with its phosphorylation state, Activates the GEF activity of SPATA13 and ARHGEF4, Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex, It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization, Plays a role in hepatocyte growth factor (HGF)-induced cell migration, Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator, Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells, Tumor suppressor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names APC, Adenomatous polyposis coli protein, BTPS2, DP2, DP2, DP3, Deleted in polyposis 2, PPP1R46, Protein APC, 5, 5, GS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAdenomatous Polyposis Coli
Short nameAdenomatous Polyposis Coli Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAdenomatous Polyposis Coli (Antibody to)
Alternative techniqueantibodies
Identity 24036
Gene APC2
Long gene name APC2, WNT signaling pathway regulator
Synonyms gene name adenomatosis polyposis coli 2
Synonyms APCL
Synonyms name adenomatous polyposis coli like
Locus 19p13, 3
Discovery year 2004-03-18
Entrez gene record 10297
Pubmed identfication 9823329 10021369
RefSeq identity NM_005883
Classification Armadillo repeat containing
Havana BLAST/BLAT OTTHUMG00000180059

Similar products

Subscribe to our Newsletter