| Long name | ADRB2 (Ser346) Primary Polyclonal Antibody |
| Also known as | ADRB2 (Ser346) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ADRB2 Ser346 |
| Specificity | This is a highly specific antibody against ADRB2 Ser346 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser346 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 330-380/413 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser346 |
| Gene ID number | 154 |
| Swiss Prot | P07550 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine, Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ADRB2, ADRB2R, ADRBR, B2AR, BETA2AR, Beta-2 adrenergic receptor, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, BAR |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ADRB2 (Ser346) |
| Short name | ADRB2 (Ser346) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | surface (Ser346) (Antibody to), adrenoceptor b 2 |
| Alternative technique | antibodies |
| Alternative to gene target | ADRB2 and IDBG-52685 and ENSG00000169252 and 154, ADRB2 and IDBG-648668 and ENSBTAG00000002144 and 281605, ADRB2R and ADRBR and B2AR and BAR and BETA2AR, Adrb2 and IDBG-152615 and ENSMUSG00000045730 and 11555, norepinephrine binding, nuclei, surface, this GO :0001993 and regulation of systemic arterial blood pressure by norepinephrine-epinephrine and biological process this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0002032 and desensitization of G-protein coupled receptor protein signaling pathway by arrestin and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004941 and beta2-adrenergic receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0008179 and adenylate cyclase binding and molecular function this GO :0008333 and endosome to lysosome transport and biological process this GO :0009409 and response to cold and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031649 and heat generation and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042312 and regulation of vasodilation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045453 and bone resorption and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051380 and norepinephrine binding and molecular function this GO :0071875 and adrenergic receptor signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004941: beta2-adrenergic receptor activity and also this GO :0005515: protein binding and also this GO :0008179: adenylate cyclase binding and also this GO :0015459: potassium channel regulator activity and also this GO :0019899: enzyme binding and also this GO :0042803: protein homodimerization activity and also this GO :0051380: norepinephrine binding, this GO :0004941: beta2-adrenergic receptor activity, this GO :0005515: protein binding, this GO :0008179: adenylate cyclase binding, this GO :0015459: potassium channel regulator activity, this GO :0019899: enzyme binding, this GO :0042803: protein homodimerization activity, this GO :0051380: norepinephrine binding, adrenoceptor beta 2 |
| Identity | 286 |
| Gene | ADRB2 |
| Long gene name | adrenoceptor beta 2 |
| Synonyms gene | ADRB2R |
| Synonyms gene name | adrenergic, beta-2-, receptor, surface , surface adrenoceptor beta 2 |
| Synonyms | ADRBR BAR B2AR |
| Locus | 5q32 |
| Discovery year | 1990-09-10 |
| GenBank acession | AF022953 |
| Entrez gene record | 154 |
| RefSeq identity | NM_000024 |
| Classification | Adrenoceptors |
| Havana BLAST/BLAT | OTTHUMG00000129933 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue